Sappanchalcone from Caesalpinia sappan L., the Proposed Biosynthetic Precursor of Brazilin
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چکیده
منابع مشابه
Contact dermatitis caused by brazilin in Caesalpinia sappan.
A 49-year-old woman presented with an eczematous reaction on her hands that which had appeared 5 days previously. To treat her wrist sprain, she had applied hot compresses with a herbal water decoction of multi-ingredient formulations on her hands for half an hour, and bathed her hands in this decoction for another 20min. After 1 day, her hands became erythematous, with burning and itching (Fig...
متن کاملBrazilin Isolated from Caesalpinia sappan suppresses nuclear envelope reassembly by inhibiting barrier-to-autointegration factor phosphorylation.
To date, many anticancer drugs have been developed by directly or indirectly targeting microtubules, which are involved in cell division. Although this approach has yielded many anticancer drugs, these drugs produce undesirable side effects. An alternative strategy is needed, and targeting mitotic exit may be one alternative approach. Localization of phosphorylated barrier-to-autointegration fa...
متن کاملBrazilin isolated from Caesalpinia sappan L. inhibits rheumatoid arthritis activity in a type-II collagen induced arthritis mouse model
BACKGROUND Caesalpinia sappan L. extracts exhibit great therapeutic potential, and have been shown to have analgesic and anti-inflammatory properties. This study aimed to understand the anti-rheumatoid activity of brazilin that was isolated from ethyl acetate extract of C. sappan L. The evaluations were conducted in mice with type-II collagen-induced arthritis (CIA). METHODS Brazilin was puri...
متن کاملA new 3-benzylchroman derivative from Sappan Lignum (Caesalpinia sappan).
3'-Deoxy-4-O-methylepisappanol, a new 3-benzylchroman derivative, was isolated from Sappan Lignum, together with thirteen known chemical compounds identified as protosappanin A, sappanchalcone, sappanone B, palmitic acid, (+)-(8S,8'S)-bisdihydrosiringenin, brazilein, 3-deoxysappanchalcone, (+)-lyoniresinol, 3-deoxysappanone B, protosappanin B, isoprotosappanin B, 3'-O-methylbrazilin and brazili...
متن کاملOne-step isolation of sappanol and brazilin from Caesalpinia sappan and their effects on oxidative stress-induced retinal death
Caesalpinia sappan is a well-distributed plant that is cultivated in Southeast Asia, Africa, and the Americas. C. sappan has been used in Asian folk medicine and its extract has been shown to have pharmacological effects. Two homoisoflavonoids, sappanol and brazilin, were isolated from C. sappan by using centrifugal partition chromatography (CPC), and tested for protective effects against retin...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1984
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.104.9_935